https://endoverdose.net/

The only real hoop you have to jump through is to go through the online training course which takes about 30 minutes and is all about administration of the drug

I received my package today and feel it’s important to have around with the current rise in opioid overdoses.

Their kit does not include CPR masks so I recommend purchasing some to keep with your doses. (Won’t share a link due to Amazon boycott)

I would’ve bought some ages ago if I lived in a bigger city.

  • Hylactor@sopuli.xyz
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    22 hours ago

    You should also know that one dose often isn’t enough, and they may re-overdose when it wears off, so at the very least stay with them until emergency services show up. Also, there is a moderate chance they will be violent when you resuscitate them, so be weary. Do not get on your knees for example, keep at least one foot planted so that you can rapidly extricate yourself if they come up angry.

    • amino@lemmy.blahaj.zone
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      11 hours ago

      I recommend watching Juno’s entire playlist on naloxone harm reduction. they’re a harm reduction educator and substance user and they have more intimate knowledge than the sterile pamphlets that medical institutions put out.

      people often get agitated because you’re forcing them into acute opioid withdrawal by administering too much naloxone. the nasal type that most civilians have access to contains 4 mg vs the 0.4 mg intramuscular that EMS workers administer. this comes out to a 5 times higher dose than strictly necessary. source:

      Based on a relative bioavailability of 50%, an initial 2 mg Naloxone Hydrochloride Nasal Spray dose would be considered equivalent to 1 mg IM dose and a 4 mg Naloxone Hydrochloride Nasal Spray dose would be equivalent to 2 mg IM dose, which corresponds with the maximum recommended initial dose in adult clinical guidelines.

      I can’t say there’s an easy alternative but anyone who’s able should contact harm reduction orgs to get trained in administering intramuscular naloxone. nasal works too, but be mindful that the person you’re “helping” is gonna have probably the worst day of their life.

      people should also be aware there’s a lot of seemingly helpful information out there influenced by copaganda warning civilians that substance users are dangerous/violent and to stay away/call the cops. this is a fucked up way to do harm reduction and really dehumanizing to substance users.

      edit: replaced precipitated withdrawal with acute opioid withdrawal.

      • cubism_pitta@lemmy.worldOP
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        2 hours ago

        Great advice, the site covers this.

        Just to note that injections bring their own risks and require additional training.

        Nasal Nalaxone doses are much higher to make them easier to administer and to ensure the Nalxone can make it though the mucus membrane.

        If you give Nalaxone / Narcan to an experienced opioid user (someone with chemical dependency) Be ready to run as they could come out of it VERY mad. They are going to miserable, sick and until the Nalaxone is gone not going to be able to relieve their symptoms.

        • amino@lemmy.blahaj.zone
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          2 hours ago

          I would argue just like Juno did that the naloxone dose being too high has nothing to do with ease of administration as that’s already ensured by the spray being so easy to use. it looks more like severe negligence and ableism from the pharma companies to me.

          as far as I understand, accounting for the nasal route only having 50% bioavailability, shouldn’t a nasal spray have a maximum of 0.8 mg of naloxone? Juno said that there are people working on putting lower doses on the market for general distribution.

          they also mention that it’s possible to stop the overdose without ruining someone’s high but that probably requires more educated training than most harm reduction resources offer. sounds to me like people are shifting blame from themselves forcing someone into withdrawal to the substance user being “violent” (this is extremely rare and mostly a rumor started by copaganda and ableist healthcare workers).