You probably haven’t heard of cardiologist Don Poldermans, but experts who study scientific misconduct believe that thousands of people may be dead because of him.
Poldermans was a prolific medical researcher at Erasmus Medical Center in the Netherlands, where he analyzed the standards of care for cardiac events after surgery, publishing a series of definitive studies from 1999 until the early 2010s.
One crucial question he studied: Should you give patients a beta blocker, which lowers blood pressure, before certain surgeries? Poldermans’s research said yes. European medical guidelines (and to a lesser extent US guidelines) recommended it accordingly.
The problem? Poldermans’s data was reportedly fake. A 2012 inquiry by Erasmus Medical School, his employer, into allegations of misconduct found that he “used patient data without written permission, used fictitious data and… submitted to conferences [reports] which included knowingly unreliable data.” Poldermans admitted the allegations and apologized, while stressing that the use of fictitious data was accidental.
Agreed, seems like a no-brainer. Typically this stuff is handled at an institutional level, with bad professors losing/ failing to achieve tenure. But some results have much bigger implications than just “Uh oh, I cited that paper and it was a bad one.” Often, entire clinical pipelines are developed off of bad research, which wastes millions of dollars.
See also, the recent scandals in Alzheimer’s research. https://www.science.org/content/article/potential-fabrication-research-images-threatens-key-theory-alzheimers-disease